Description:
EASI-DSR Capsule is a dual-acting formulation combining Esomeprazole, a potent proton pump inhibitor (PPI), and Domperidone, a prokinetic agent. This unique combination offers rapid and long-lasting relief from symptoms of acid reflux, gastritis, GERD, dyspepsia, and nausea by reducing gastric acid secretion and improving gastrointestinal motility.
Mechanism of Action:
- Esomeprazole irreversibly inhibits the H⁺/K⁺-ATPase enzyme in gastric parietal cells, thereby suppressing acid secretion at the final step of acid production.
- Domperidone acts as a dopamine D₂-receptor antagonist that enhances gastric motility, accelerates gastric emptying, and prevents reflux by increasing lower esophageal sphincter tone.
Therapeutic Indications:
- Gastroesophageal Reflux Disease (GERD)
- Peptic Ulcer Disease
- Zollinger-Ellison Syndrome
- Dyspepsia / Acid Indigestion
- Nausea & Vomiting associated with reflux
- Heartburn and epigastric discomfort
Safety Information:
- Contraindicated in patients with known hypersensitivity to PPIs or Domperidone.
- Use with caution in hepatic impairment or long-term therapy.
- Avoid concomitant use with strong CYP3A4 inhibitors.
- Pregnancy & lactation: Use only if clearly needed and prescribed by a physician.










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